aphranel

Our Solutions

Aphranel® MagiCCrystal Novo

Precision Structural Support. Regeneration Over Time.

Modern aesthetic medicine is no longer defined by immediate transformation alone. Increasingly, both patients and physicians are seeking regenerative solutions that respect individuality, support natural aging, and deliver results that evolve gracefully over time.


Aphranel® MagiCCrystal Novo is a regenerative CaHA (Calcium Hydroxyapatite)-based injectable filler designed for structural support, contour enhancement, and collagen regeneration. Developed with a dual-regeneration mechanism and a structural system composed of 30% CaHA microspheres and 70% CMC gel carrier, it provides immediate structural support while supporting progressive collagen regeneration.


As structure and regeneration work together over time, Aphranel® helps create aesthetic outcomes that are balanced, natural-looking, and enduring.

Aphranel MagiCCrystal Novo three dimensions of regenerative aesthetics: Immediate Shaping, Evolving Regeneration, and Controlled Degradation — Beauty Exists Across Time, Shape · Regenerate · Evolve

Composition

Dual-Regeneration Structural System: Developed with a dual-regeneration mechanism and a structural system composed of 30% CaHA microspheres and 70% CMC gel carrier, Aphranel® MagiCCrystal Novo provides immediate structural support while supporting progressive collagen regeneration.


Over time, structural refinement and natural collagen regeneration work in harmony, delivering aesthetic outcomes that are balanced, natural-looking, and long-lasting.


30% CaHA Microspheres:Designed to provide structural support and biostimulatory activity, the CaHA microspheres are engineered with a controlled particle size distribution of approximately 30–35 μm, supporting tissue integration and collagen regeneration.


70% CMC Gel Carrier:Acts as a carrier matrix to ensure smooth injectability, uniform microsphere distribution, and stable product placement, while supporting controlled biodegradation over time.

Aphranel MagiCCrystal Novo dual-regeneration structural system: 30 percent CaHA microspheres plus 70 percent CMC gel carrier composition diagram

Core Technologies

ACD-MT® PATENTED MICROSPHERE TECHNOLOGY:

Accurate Controllable Degradation

Microsphere Technology

ACD-MT patented microsphere technology overview: Uniform Particle Size 30 to 35 microns, Large Specific Surface Area for fibroblast growth, Raspberry-Shaped Surface for cell adhesion, Through-Hole Structure for controlled biodegradation

PCD-ETT® PATENTED CMC GEL TECHNOLOGY:

Physical Crosslinking Dynamic

Entanglement Topology Technology

PCD-ETT CMC gel technology: No cross-linking agents, designed for gradual biodegradation without residual materials
PCD-ETT CMC gel technology: Uniformly distributed microspheres for smooth injection and precise placement
PCD-ETT CMC gel technology: High G prime viscoelasticity at 5500 Pascals for strong structural support and stable contouring
PCD-ETT CMC gel technology: Close to human osmotic pressure at approximately 299 milliosmoles per kilogram to reduce post-procedure swelling and improve injection comfort
HOW IT WORKS

Mechanism of Action

Aphranel MagiCCrystal Novo 7-step mechanism of action: 1. Before Treatment with collagen and volume loss, 2. Injection of 17 million CaHA microspheres in CMC gel, 3. Immediate Structural Support from gel carrier, 4. Progressive Carrier Resorption, 5. Collagen Regeneration via fibroblast stimulation, 6. Controlled Biodegradation of microspheres, 7. Long-Term natural-looking results from regenerated collagen

Global Certifications

Aphranel MagiCCrystal Novo global certifications: China Class III Medical Device Certification, European Union MDR Certification, Saudi Arabia SFDA Certification

Case Interaction